Kristin Sellers, PhD

Assistant Adjunct Professor
Neurological Surgery
[email protected]

Kristin Sellers is an Associate Professional Researcher in the Chang Lab. She completed her Ph.D. in Neurobiology at UNC-Chapel Hill and a post-doc in the Chang Lab from 2016 to 2020 working on the DARPA-funded SUBNETS project. Her work focuses on using neural activity to inform DBS implant location and closed-loop stimulation in clinical-trials patients and novel neurotechnologies, including new probe and device designs for use in humans. She also contributes to a community effort to adopt standardized data formats to enable easy data sharing and archiving.

Publications: 

Large-scale single-neuron speech sound encoding across the depth of human cortex.

Nature

Leonard MK, Gwilliams L, Sellers KK, Chung JE, Xu D, Mischler G, Mesgarani N, Welkenhuysen M, Dutta B, Chang EF

DREDge: robust motion correction for high-density extracellular recordings across species.

bioRxiv : the preprint server for biology

Windolf C, Yu H, Paulk AC, Meszéna D, Muñoz W, Boussard J, Hardstone R, Caprara I, Jamali M, Kfir Y, Xu D, Chung JE, Sellers KK, Ye Z, Shaker J, Lebedeva A, Raghavan M, Trautmann E, Melin M, Couto J, Garcia S, Coughlin B, Horváth C, Fiáth R, Ulbert I, Movshon JA, Shadlen MN, Churchland MM, Churchland AK, Steinmetz NA, Chang EF, Schweitzer JS, Williams ZM, Cash SS, Paninski L, Varol E

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder.

Journal of visualized experiments : JoVE

Sellers KK, Khambhati AN, Stapper N, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD

Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans.

Brain Stimulation

Fan JM, Lee AM, Sellers KK, Woodworth K, Makhoul GS, Liu TX, Henderson C, Astudillo Maya DA, Martinez R, Zamanian H, Speidel BA, Khambhati AN, Rao VR, Sugrue LP, Scangos KW, Chang EF, Krystal AD

Closed-loop neurostimulation for the treatment of psychiatric disorders.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Sellers KK, Cohen JL, Khambhati AN, Fan JM, Lee AM, Chang EF, Krystal AD

Epileptiform discharges triggered with direct electrical stimulation for treatment-resistant depression: Factors that modulate risk and treatment considerations.

Brain Stimulation

Fan JM, Khambhati AN, Sellers KK, Stapper N, Maya DA, Kunwar E, Henderson C, Sugrue LP, Scangos KW, Chang EF, Rao VR, Krystal AD

Changes in intracranial neurophysiology associated with acute COVID-19 infection.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

Sellers KK, Stapper N, Astudillo Maya DA, Henderson C, Khambhati AN, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD

High-density single-unit human cortical recordings using the Neuropixels probe.

Neuron

Chung JE, Sellers KK, Leonard MK, Gwilliams L, Xu D, Dougherty ME, Kharazia V, Metzger SL, Welkenhuysen M, Dutta B, Chang EF

Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain.

Frontiers in neuroscience

Prosky J, Cagle J, Sellers KK, Gilron R, de Hemptinne C, Schmitgen A, Starr PA, Chang EF, Shirvalkar P

Closed-loop neuromodulation in an individual with treatment-resistant depression.

Nature medicine

Scangos KW, Khambhati AN, Daly PM, Makhoul GS, Sugrue LP, Zamanian H, Liu TX, Rao VR, Sellers KK, Dawes HE, Starr PA, Krystal AD, Chang EF

Thin-film microfabrication and intraoperative testing of µECoG and iEEG depth arrays for sense and stimulation.

Journal of neural engineering

Sellers KK, Chung JE, Zhou J, Triplett MG, Dawes HE, Haque RU, Chang EF

Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.

Frontiers in human neuroscience

Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA

Bidirectional propagation of low frequency oscillations over the human hippocampal surface.

Nature communications

Kleen JK, Chung JE, Sellers KK, Zhou J, Triplett M, Lee K, Tooker A, Haque R, Chang EF