Prasad Shirvalkar, MD, PhD

Assistant Clinical Professor
Assistant Professor Department of Anesthesiology (Pain Management) Department of Neurology UCSF School of Medicine
+1 415 885-7246

Dr. Prasad Shirvalkar is the Principal Investigator of UCSF Clinical Trials for refractory chronic pain (NCT03029884 and NCT04144972) and a neurologist and interventional pain medicine specialist at the UCSF Pain Management Center at Mount Zion. He provides the full spectrum of care for chronic pain conditions, including conservative, nonsurgical treatments such as medications and nerve blocks (anesthetic injections near nerves that are sending pain signals). He also treats patients with advanced neuromodulation therapy by implanting peripheral and spinal cord stimulators, which are devices that relieve pain by sending electrical signals to the spine.

Shirvalkar cares for hospitalized patients and provides telemedicine visits for established patients. He coordinates with other providers for each patient, collaborating to treat any pain condition.

Shirvalkar's research aims to develop new therapies for hard-to-treat pain disorders, such as post-stroke pain and phantom limb pain, by harnessing technologies such as brain and spinal cord stimulation. He is conducting a study using electrodes implanted in the brain to understand how individuals interpret pain signals, with the goal of personalizing brain stimulation therapies. He is also interested in how sudden, severe pain episodes can progress to become chronic and in whether early intervention can prevent chronic pain.

Shirvalkar earned his doctoral and medical degrees at Icahn School of Medicine at Mount Sinai. He then completed a residency in neurology at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center, where he served as chief resident. He completed a fellowship in pain management at UCSF.

Shirvalkar belongs to the American Academy of Neurology, American Pain Association, American Pain Society, American Society of Anesthesiologists, International Neuromodulation Society and North American Neuromodulation Society, where he serves on the scientific program committee.

In addition to medicine and science, Shirvalkar has a passion for percussion. He plays jazz drums in his free time and used to play with the Oakland Raiders' band.

Publications: 

Epidural Spinal Electrogram Provides Direct Spinal Recordings in Awake Human Participants.

Frontiers in human neuroscience

Burke JF, Kunwar N, Yaroshinsky MS, Louie KH, Shirvalkar P, Su P, Henry M, Pasvankas G, Poree L, Jacques L, Wang DD

Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.

Frontiers in human neuroscience

Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS

High-Frequency Impulse Therapy for Treatment of Chronic Back Pain: A Multicenter Randomized Controlled Pilot Study.

Journal of pain research

Amirdelfan K, Hong M, Tay B, Reddy S, Reddy V, Yang M, Khanna K, Shirvalkar P, Abrecht C, Gulati A

Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.

Frontiers in human neuroscience

Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA

Emerging Therapies for the Treatment of Complex Regional Pain Syndrome.

Po-Yi Paul Su, Shikha Sharma, Prasad Shirvalkar, Lawrence Poree

Musical Hallucinations in Chronic Pain: The Anterior Cingulate Cortex Regulates Internally Generated Percepts.

Frontiers in neurology

Schmitgen A, Saal J, Sankaran N, Desai M, Joseph I, Starr P, Chang EF, Shirvalkar P

Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.

Frontiers in human neuroscience

Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS

A Tale of Two Cords: Diastematomyelia.

Pain Medicine

Westin Tom, Thoha Pham, Prasad Shirvalkar

A Deep Brain Stimulation Trial Period for Treating Chronic Pain.

Journal of clinical medicine

Shirvalkar P, Sellers KK, Schmitgen A, Prosky J, Joseph I, Starr PA, Chang EF

A Comprehensive Practice Guideline for Magnetic Resonance Imaging Compatibility in Implanted Neuromodulation Devices.

Neuromodulation : journal of the International Neuromodulation Society

Sayed D, Chakravarthy K, Amirdelfan K, Kalia H, Meacham K, Shirvalkar P, Falowski S, Petersen E, Hagedorn JM, Pope J, Leever J, Deer T

Transcranial Magnetic Stimulation for Pain, Headache, and Comorbid Depression: INS-NANS Expert Consensus Panel Review and Recommendation.

Neuromodulation : journal of the International Neuromodulation Society

Leung A, Shirvalkar P, Chen R, Kuluva J, Vaninetti M, Bermudes R, Poree L, Wassermann EM, Kopell B, Levy R

Large expert-curated database for benchmarking document similarity detection in biomedical literature search.

Database

eter Brown, Aik-Choon Tan, Mohamed A El-Esawi, Thomas Liehr, Oliver Blanck, Douglas P Gladue, Gabriel M F Almeida, Tomislav Cernava, Carlos O Sorzano, Andy W K Yeung, Michael S Engel, Arun Richard Chandrasekaran, Thilo Muth, Martin S Staege, Swapna V Daulatabad, Darius Widera, Junpeng Zhang, Adrian Meule, Ken Honjo, Olivier Pourret, Cong-Cong Yin, Zhongheng Zhang, Marco Cascella, Willy A Flegel, Carl S Goodyear, Mark J van Raaij, Zuzanna Bukowy-Bieryllo, Luca G Campana, Nicholas A Kurniawan, David Lalaouna, Felix J Hüttner, Brooke A Ammerman, Felix Ehret, Paul A Cobine, Ene-Choo Tan, Hyemin Han, Wenfeng Xia, Christopher McCrum, Ruud P M Dings, Francesco Marinello, Henrik Nilsson, Brett Nixon, Konstantinos Voskarides, Long Yang, Vincent D Costa, Johan Bengtsson-Palme, William Bradshaw, Dominik G Grimm, Nitin Kumar, Elvis Martis, Daniel Prieto, Sandeep C Sabnis, Said E D R Amer, Alan W C Liew, Paul Perco, Farid Rahimi, Giuseppe Riva, Chongxing Zhang, Hari P Devkota, Koichi Ogami, Zarrin Basharat, Walter Fierz, Robert Siebers, Kok-Hian Tan, Karen A Boehme, Peter Brenneisen, James A L Brown, Brian P Dalrymple, David J Harvey, Grace Ng, Sebastiaan Werten, Mark Bleackley, Zhanwu Dai, Raman Dhariwal, Yael Gelfer, Marcus D Hartmann, Pawel Miotla, Radu Tamaian, Pragashnie Govender, Oliver J Gurney-Champion, Joonas H Kauppila, Xiaolei Zhang, Natalia Echeverría, Santhilal Subhash, Hannes Sallmon, Marco Tofani, Taeok Bae, Oliver Bosch, Páraic O Cuív, Antoine Danchin, Barthelemy Diouf, Tuomas Eerola, Evangelos Evangelou, Fabian V Filipp, Hannes Klump, Lukasz Kurgan, Simon S Smith, Olivier Terrier, Neil Tuttle, David B Ascher, Sarath C Janga, Leon N Schulte, Daniel Becker, Christopher Browngardt, Stephen J Bush, Guillaume Gaullier, Kazuki Ide, Clement Meseko, Gijsbert D A Werner, Jan Zaucha, Abd A Al-Farha, Noah F Greenwald, Segun I Popoola, Shaifur Rahman, Jialin Xu, Sunny Y Yang, Noboru Hiroi, Ozgul M Alper, Chris I Baker, Michael Bitzer, George Chacko, Birgit Debrabant, Ray Dixon, Evelyne Forano, Matthew Gilliham, Sarah Kelly, Karl-Heinz Klempnauer, Brett A Lidbury, Michael Z Lin, Iseult Lynch, Wujun Ma, Edward W Maibach, Diane E Mather, Kutty S Nandakumar, Robert S Ohgami, Piero Parchi, Patrizio Tressoldi, Yu Xue, Charles Armitage, Pierre Barraud, Stella Chatzitheochari, Luis P Coelho, Jiajie Diao, Andrew C Doxey, Angélique Gobet, Pingzhao Hu, Stefan Kaiser, Kate M Mitchell, Mohamed F Salama, Ivan G Shabalin, Haijun Song, Dejan Stevanovic, Ali Yadollahpour, Erliang Zeng, Katharina Zinke, C G Alimba, Tariku J Beyene, Zehong Cao, Sherwin S Chan, Michael Gatchell, Andreas Kleppe, Marcin Piotrowski, Gonzalo Torga, Adugna A Woldesemayat, Mehmet I Cosacak, Scott Haston, Stephanie A Ross, Richard Williams, Alvin Wong, Matthew K Abramowitz, Andem Effiong, Senhong Lee, Muhammad Bilal Abid, Cyrus Agarabi, Cedric Alaux, Dirk R Albrecht, Gerald J Atkins, Charles R Beck, A M J J Bonvin, Emer Bourke, Thomas Brand, Ralf J Braun, James A Bull, Pedro Cardoso, Dee Carter, Robin M Delahay, Bernard Ducommun, Pascal H G Duijf, Trevor Epp, Eeva-Liisa Eskelinen, Mazyar Fallah, Debora B Farber, Jose Fernandez-Triana, Frank Feyerabend, Tullio Florio, Michael Friebe, Saori Furuta, Mads Gabrielsen, Jens Gruber, Malgorzata Grybos, Qian Han, Michael Heinrich, Heikki Helanterä, Michael Huber, Albert Jeltsch, Fan Jiang, Claire Josse, Giuseppe Jurman, Haruyuki Kamiya, Kim de Keersmaecker, Erik Kristiansson, Frank-Erik de Leeuw, Jiuyong Li, Shide Liang, Jose A Lopez-Escamez, Francisco J Lopez-Ruiz, Kevin J Marchbank, Rolf Marschalek, Carmen S Martín, Adriana E Miele, Xavier Montagutelli, Esteban Morcillo, Rosario Nicoletti, Monika Niehof, Ronan O’Toole, Toshihiko Ohtomo, Henrik Oster, Jose-Alberto Palma, Russell Paterson, Mark Peifer, Maribel Portilla, M C Portillo, Antonia L Pritchard, Stefan Pusch, Gajendra P S Raghava, Nicola J Roberts, Kehinde Ross, Birgitt Schuele, ...

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain.

Frontiers in computational neuroscience

Shirvalkar P, Veuthey TL, Dawes HE, Chang EF

List of Contributors of Volume 2.

Neuromodulation

Al-Kaisy Adnan, Andreas Alexopoulos, Kenneth M. Alo, Ron L. Alterman, Arun Amar, Pablo Andrade, Sailesh Arulkumar, Ahmed J. Awad, Gordon Baltuch, Giancarlo Barolat, Ernest J. Barthélemy, Neil U. Barua, Maria E. Bennett, Nicole Bentley, Yarema B. Bezchlibnyk, Kelly R. Bijanki, William Bingaman, Joseph W. Boggs, Paul Boon, Brigitte A. Brouwer, Lucas W. Campos, Anthony Caparso, Annamaria Capozzo, John Chae, Jin Woo Chang, Jennifer Cheng, David Copenhaver, Timothy R. Deer, Milind Deogaonkar, Deepali Dhar, Keeley Dohmeier, Darin D. Dougherty, Dominique M. Durand, Kelly Foote, Jeffrey Gilligan, Steven S. Gill, Jorge Gonzalez-Martinez, Benjamin D. Greenberg, Robert E. Gross, Michael H. Pourfar, Clement Hamani, Salim M. Hayek, Paul E. Holtzheimer, Brian M. Ilfeld, Haiyan Jin, Bert Joosten, Na Young Jung, Chong H. Kim, Young Goo Kim, Martin Klehr, Paul Koch, Sina Kohl, Brian H. Kopell, Daniel Kramer, Elliot S. Krames, Balu Krishnan, Vibhor Krishna, Jens Kuhn, Jason Kyung-soo Hong, Kapural Leonardo, Michael S. Leong, Dianyou Li, Andreas A. Linninger, Nir Lipsman, Charles Liu, Andres M. Lozano, Michael Mackow, Mark N. Malinowski, Helen S. Mayberg, Paolo Mazzone, Ankit I. Mehta, Vivek Mehta, Reversa Mills-Joseph, Dileep Nair, Richard B. North, Michael Okun, Nikunj K. Patel, Parag G. Patil, Jason E. Pope, Lawrence R. Poree, Joshua P. Prager, Robrecht Raedt, Jonathan J. Rasouli, Serge Rasskazoff, Richard Rauck, Kevin Reeves, Ali R. Rezai, Jonathan Russin, Abraham Sabersky, Michael Saulino, Eugenio Scarnati, Stefan Schu, Mayur Sharma, Jane Shipley, Prasad Shirvalkar, Konstantin V. Slavin, Michael Stanton-Hicks, Scellig Stone, William A. Stuart, Bomin Sun, Kevin Tangen, Stewart J. Tepper, Maarten van Kleef, Tim Vancamp, Paul Verrills, Fabio Viselli, Veerle Visser-Vandewalle, Flora Vitale, Kristl Vonck, Tao Wang, Xuelian Wang, Richard L. Weiner, Alik S. Widge, Amorn Wongsarnpigoon, Alon Y. Mogilner, Kurt A. Yaeger, Tony L. Yaksh, Dali Yin, Kristina Zeljic, Chencheng Zhang, Shikun Zhan

Improving lower limb strength in incomplete spinal cord injury with non-invasive spinal associative stimulation.

Brain Stimulation

M. Cortes, G. Thickbroom, J. Valls-Sole, P. Shirvalkar, A. Pascual-Leone, D. Edwards

American neuroborreliosis presenting as cranial polyneuritis and radiculoneuritis.

Neurology(R) neuroimmunology & neuroinflammation

Wang E, Shirvalkar PR, Maciel CB, Merkler AE, Safdieh J, Gupta A

Memory-guided learning: CA1 and CA3 neuronal ensembles differentially encode the commonalities and differences between situations.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Bahar AS, Shirvalkar PR, Shapiro ML

Memory modulates journey-dependent coding in the rat hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ferbinteanu J, Shirvalkar P, Shapiro ML

Infrageniculate Interventions in Female Patients: Improved Patency Rates but Higher Rates of Postoperative Complications.

Journal of Vascular Surgery

Tejas R. Shah, Angeliki Vouyouka, Daniel K. Han, Sharif Ellozy, Robert Lookstein, Prasad Shirvalkar, Michael Marin, Peter L. Faries

Bidirectional changes to hippocampal theta-gamma comodulation predict memory for recent spatial episodes.

Proceedings of the National Academy of Sciences of the United States of America

Shirvalkar PR, Rapp PR, Shapiro ML

The multiple origins and laminar topography of the hippocampal theta rhythm.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Shirvalkar P, Bahar AS

Hippocampal neural assemblies and conscious remembering.

Journal of neurophysiology

Shirvalkar PR

Cognitive enhancement with central thalamic electrical stimulation.

Proceedings of the National Academy of Sciences of the United States of America

Shirvalkar P, Seth M, Schiff ND, Herrera DG

Regulation of neurogenesis in the aging vertebrate brain: role of oxidative stress and neuropsychiatric factors.

Clinical Neuroscience Research

Evelyn Kim, Prasad Shirvalkar, Daniel G. Herrera