Kristin Sellers, PhD

Assistant Adjunct Professor

M_NeuSrg-General

Kristin Sellers is an Associate Professional Researcher in the Chang Lab. She completed her Ph.D. in Neurobiology at UNC-Chapel Hill and a post-doc in the Chang Lab from 2016 to 2020 working on the DARPA-funded SUBNETS project. Her work focuses on using neural activity to inform DBS implant location and closed-loop stimulation in clinical-trials patients and novel neurotechnologies, including new probe and device designs for use in humans. She also contributes to a community effort to adopt standardized data formats to enable easy data sharing and archiving.

Publications

Best practices for clinical trials of deep brain stimulation for neuropsychiatric indications.

Frontiers in human neuroscience

Tremblay-McGaw AG, Hamlat EJ, Becker NC, Astudillo Maya DA, Krystal AD, Sellers KK

Invasive Brain Mapping Identifies Personalized Therapeutic Neuromodulation Targets for Obsessive-Compulsive Disorder.

medRxiv : the preprint server for health sciences

Lee AM, Kist A, Alvarez J, Sellers KK, Khambhati AN, Sugrue LP, Reid LB, Kadlec K, Fan JM, Allawala AB, Racine CA, Norbu T, Astudillo D, Tremblay-McGaw AG, Becker N, Alhourani A, Starr PA, Chang EF, Krystal AD

DREDge: robust motion correction for high-density extracellular recordings across species.

Nature methods

Windolf C, Yu H, Paulk AC, Meszéna D, Muñoz W, Boussard J, Hardstone R, Caprara I, Jamali M, Kfir Y, Xu D, Chung JE, Sellers KK, Ye Z, Shaker J, Lebedeva A, Raghavan RT, Trautmann E, Melin M, Couto J, Garcia S, Coughlin B, Elmaleh M, Christianson D, Greenlee JDW, Horváth C, Fiáth R, Ulbert I, Long MA, Movshon JA, Shadlen MN, Churchland MM, Churchland AK, Steinmetz NA, Chang EF, Schweitzer JS, Williams ZM, Cash SS, Paninski L, Varol E

Large-scale single-neuron speech sound encoding across the depth of human cortex.

Nature

Leonard MK, Gwilliams L, Sellers KK, Chung JE, Xu D, Mischler G, Mesgarani N, Welkenhuysen M, Dutta B, Chang EF

DREDge: robust motion correction for high-density extracellular recordings across species.

bioRxiv : the preprint server for biology

Windolf C, Yu H, Paulk AC, Meszéna D, Muñoz W, Boussard J, Hardstone R, Caprara I, Jamali M, Kfir Y, Xu D, Chung JE, Sellers KK, Ye Z, Shaker J, Lebedeva A, Raghavan M, Trautmann E, Melin M, Couto J, Garcia S, Coughlin B, Horváth C, Fiáth R, Ulbert I, Movshon JA, Shadlen MN, Churchland MM, Churchland AK, Steinmetz NA, Chang EF, Schweitzer JS, Williams ZM, Cash SS, Paninski L, Varol E

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder.

Journal of visualized experiments : JoVE

Sellers KK, Khambhati AN, Stapper N, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD

Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans.

Brain Stimulation

Fan JM, Lee AM, Sellers KK, Woodworth K, Makhoul GS, Liu TX, Henderson C, Astudillo Maya DA, Martinez R, Zamanian H, Speidel BA, Khambhati AN, Rao VR, Sugrue LP, Scangos KW, Chang EF, Krystal AD

Closed-loop neurostimulation for the treatment of psychiatric disorders.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Sellers KK, Cohen JL, Khambhati AN, Fan JM, Lee AM, Chang EF, Krystal AD

Epileptiform discharges triggered with direct electrical stimulation for treatment-resistant depression: Factors that modulate risk and treatment considerations.

Brain Stimulation

Fan JM, Khambhati AN, Sellers KK, Stapper N, Maya DA, Kunwar E, Henderson C, Sugrue LP, Scangos KW, Chang EF, Rao VR, Krystal AD

Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.

Frontiers in human neuroscience

Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA

Bidirectional propagation of low frequency oscillations over the human hippocampal surface.

Nature communications

Kleen JK, Chung JE, Sellers KK, Zhou J, Triplett M, Lee K, Tooker A, Haque R, Chang EF

Publications

Best practices for clinical trials of deep brain stimulation for neuropsychiatric indications.

Invasive Brain Mapping Identifies Personalized Therapeutic Neuromodulation Targets for Obsessive-Compulsive Disorder.

DREDge: robust motion correction for high-density extracellular recordings across species.

Large-scale single-neuron speech sound encoding across the depth of human cortex.

DREDge: robust motion correction for high-density extracellular recordings across species.

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder.

Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans.

Closed-loop neurostimulation for the treatment of psychiatric disorders.

Epileptiform discharges triggered with direct electrical stimulation for treatment-resistant depression: Factors that modulate risk and treatment considerations.

Changes in intracranial neurophysiology associated with acute COVID-19 infection.

High-density single-unit human cortical recordings using the Neuropixels probe.

Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain.

Closed-loop neuromodulation in an individual with treatment-resistant depression.

Thin-film microfabrication and intraoperative testing of µECoG and iEEG depth arrays for sense and stimulation.

Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.

Bidirectional propagation of low frequency oscillations over the human hippocampal surface.